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Main Street Inn

404 S. Main St., Galena, IL 61036

Vacation Rentals

Located on Galena's historic downtown Main Street, the Main Street Inn is a cozy, inviting place to relax that is listed on the National Register of Historic Places (circa 1850).

Main Street Inn offers 6 luxurious and spacious rooms located on the 2nd floor that will meet the needs of romantic adventures, friend getaways, or anything in between. Walk out the front door to take a stroll up Main Street and browse through Galena's unique stores and boutiques, enjoy dining at one of Galena's fine restaurants, or stop by one of our wine shops. Or stay in and simply enjoy the comforts of your room.

Whatever your reason for coming to Galena, the Main Street Inn is here for you!

What's happening nearby...

40th Annual Nouveau Parade & Celebration

Galena Cellars Wine Tasting Room •  Nov 22 @ 11AM

Galena Cellars celebrates the release of the 2024 Nouveau wine - The 40th Annual Celebration!

Read more about 40th Annual Nouveau Parade & Celebration

Galena Holiday Kickoff!

Nov 30 @ 5PM

Join in welcoming Santa to town to kick off the holiday season in Galena!

Read more about Galena Holiday Kickoff!

Galena Holidaze Festival

Green Street Plaza  •  Dec 07 @ 11PM

The Galena Holidaze Festival is bringing the magic of Christmastime to Galena, Illinois.

Read more about Galena Holidaze Festival

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