Main Street Inn
404 S. Main St., Galena, IL 61036
Vacation Rentals
Located on Galena's historic downtown Main Street, the Main Street Inn is a cozy, inviting place to relax that is listed on the National Register of Historic Places (circa 1850).
Main Street Inn offers 6 luxurious and spacious rooms located on the 2nd floor that will meet the needs of romantic adventures, friend getaways, or anything in between. Walk out the front door to take a stroll up Main Street and browse through Galena's unique stores and boutiques, enjoy dining at one of Galena's fine restaurants, or stop by one of our wine shops. Or stay in and simply enjoy the comforts of your room.
Whatever your reason for coming to Galena, the Main Street Inn is here for you!
What's happening nearby...
Galena 45th Annual Halloween Parade
Main Street, Galena • Oct 25 @ 6:30PM
Join Galena's 45th Annual Halloween Parade & Festival! The largest, longest, and spookiest Parade and Festival in the Tri-State Area!
Read more about Galena 45th Annual Halloween Parade
41st Annual Nouveau Parade & Celebration
Galena Cellars Wine Tasting Room • Nov 21 @ 11AM
Galena Cellars celebrates the release of the 2025 Nouveau wine - The 41st Annual Celebration!
Read more about 41st Annual Nouveau Parade & Celebration
Galena Holiday Kickoff!
Nov 29 @ 5PM
Join in welcoming Santa to town to kick off the holiday season in Galena!
Read more about Galena Holiday Kickoff!You might also be interested...
Galena Cellars Vineyard Two Bedroom Farmhouse
Galena
Located within walking distance of Galena's most popular vineyard, this is a perfect location for a getaway.
Read more about Galena Cellars Vineyard Two Bedroom Farmhouse
The Owl House
Galena
Originally built as a warehouse circa 1850, the Owl House has since been completely renovated into a modern and comfortable living space with industrial elements and…
Read more about The Owl House
Eagle Ridge Resort & Spa
Galena
Tucked among The Galena Territory's 6,800 rolling acres of woodlands and open countryside, Eagle Ridge Resort & Spa offers "country elegant" hotel accommodations, rental homes and…
Read more about Eagle Ridge Resort & Spa