Main Street Inn
404 S. Main St., Galena, IL 61036
Vacation Rentals
Located on Galena's historic downtown Main Street, the Main Street Inn is a cozy, inviting place to relax that is listed on the National Register of Historic Places (circa 1850).
Main Street Inn offers 6 luxurious and spacious rooms located on the 2nd floor that will meet the needs of romantic adventures, friend getaways, or anything in between. Walk out the front door to take a stroll up Main Street and browse through Galena's unique stores and boutiques, enjoy dining at one of Galena's fine restaurants, or stop by one of our wine shops. Or stay in and simply enjoy the comforts of your room.
Whatever your reason for coming to Galena, the Main Street Inn is here for you!
What's happening nearby...
42nd Annual Nouveau Parade & Celebration
Galena Cellars Wine Tasting Room • Nov 20 @ 11AM
Galena Cellars' 42nd Annual Nouveau Celebration features a festive Main Street parade, the release of the 2026 Nouveau wine, and a weekend of live music, wine…
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Galena’s Jeep Jingle
Nov 28 @ 5PM
Celebrate the start of the holiday season in Galena with the Jeep Jingle at 5 PM, Santa’s tree lighting, and an evening of treats, activities, and…
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Galena Holidaze Festival
Green Street Plaza • Dec 05 @ 11AM
The Galena Holidaze Festival is bringing the magic of Christmastime to Galena, Illinois.
Read more about Galena Holidaze FestivalYou might also be interested...
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